|
|
|
 Re: الإعلان عن بدء المرحلة الأخيرة phase3 من اخت� (Re: Elhadi)
|
وتم كذلك اليوم نشر التقرير الأولي لنتائج اختبارات المرحلة السابقة..
https://www.nejm.org/doi/full/10.1056/NEJMoa2022483https://www.nejm.org/doi/full/10.1056/NEJMoa2022483
Quote:
The mRNA-1273 vaccine induced immune responses in all participants, and no trial-limiting safety concerns were identified. These findings support further development of this vaccine
|
| |
 
|
|
|
|
|
|
|
|
Re: الإعلان عن بدء المرحلة الأخيرة phase3 من اخت� (Re: Deng)
|
Moderna will begin its late-stage trial testing a potential vaccine to prevent Covid-19 on July 27, according to a posting published Tuesday on ClinicalTrials.gov.
The trial will enroll 30,000 participants across 87 locations, according to the website. Participants in the experimental arm will receive a 100 microgram dose of the potential vaccine on the first day and another 29 days later. Some patients will also receive a placebo.
Moderna’s experimental vaccine contains genetic material called messenger RNA, or mRNA. The mRNA is a genetic code that tells cells what to build — in this case, an antigen that may induce an immune response to the virus. It became the first candidate to enter a phase one human trial in March.
In May, the company released data from its early stage trial, which showed the vaccine produced neutralizing antibodies against Covid-19 in at least eight participants. The vaccine also made binding antibodies in all participants.
The effort by Moderna is one of several working on a potential vaccine for Covid-19, which has infected more than 13 million people and killed at least 573,200 across the globe as of Tuesday, according to data compiled by Johns Hopkins University. More than 100 vaccines are under development globally, according to the World Health Organization.
Earlier this month, pharmaceutical giant Pfizer released positive results from its closely watched early stage human trial of a coronavirus vaccine.
The U.S. is aiming to deliver 300 million doses of a vaccine for Covid-19 by early 2021.
Scientists are still learning about key aspects of the virus, including how immune systems respond once a person is exposed. The answers, they say, may have important implications for vaccine development, including how quickly it can be deployed to the public.
Moderna’s stock fell earlier this month after a report said its trial would be delayed. The shares were up 4.6% in afternoon trading Tuesday.
Dr. Anthony Fauci, the nation’s top infectious disease expert, has often touted Moderna’s potential vaccine.
On Monday, he said he’s “cautiously optimistic” scientists will be able to create at least one safe and effective vaccine by the end of the year or early 2021.
https://www.cnbc.com/2020/07/14/moderna-will-begin-late-stage-coronavirus-vaccine-trial-on-july-27.htmlhttps://www.cnbc.com/2020/07/14/moderna-will-begin-late-stage-coronavirus-vaccine-trial-on-july-27.html
| |
|
|
|
|
|
|
|
|
Re: الإعلان عن بدء المرحلة الأخيرة phase3 من اخت� (Re: Deng)
|
نعم يا دينق نتائج مبشرة جداً حتى الآن..
Moderna هي اسم الشركة
واللقاح هو mRNA-1273
اللقاح هو جهد مشترك بين الشركة والـ NIH ـ National Institute of Health اللي هو جزء من Department of Health
والشركة نفسها حصلت من الحكومة الفيدرالية في شهر أبريل الماضي (يعني قبال حوالي ثلاثة أشهر من الآن) على تمويل بقيمة 483 بليون دولار لتطوير هذا اللقاح والتجارب التي أجريت عليه
| |
|
|
|
|
|
|
|
|
|
Re: الإعلان عن بدء المرحلة الأخيرة phase3 من اخت� (Re: Elhadi)
|
Moderna تخطو بثبات نحو انتاج أول لقاح ضد فيروس كورونا ..
غداً الاثنين تبدأ المرحلة الأخيرة من (phase 3) للقاح في الولايات المتحدة وسط جدل محتدم وكثيف جداً حول براءة الاختراع ـ patent ـ للتقنية الطبية (LNP) المستخدمة في مساعدة وتحفيز جسم الإنسان على إنتاج بروتينات ولقاحات علاجية خاصة به،
( الـ spike protein في هذه الحالة )
* الجدل ليس ( حول اللقاح نفسه) ولكن حول براءة الاختراع المرتبطة بطريقة عمل اللقاح نفسه أو الـ delivery method
| |
|
|
|
|
|
|
| |
Elhadi
Deng
MOHAMMED ELSHEIKH
فيس بوك
تويتر
انستقرام
يوتيوب
بنتيريست