المجمــوعة الأولى i1- Which of the following is not an indication for Tranexamic Acid ?i a- Treatment of heamorrhage associated with excessive fibrinolysis b- An antidote for Streptokinase overdose c- Prophylaxis of hereditary angioedma d- Prevent heammorhage due to Heparin overdose
i2- Which of the following drugs does not cause insomnia ?i a- MAOI’s b- Caffeine c- Beta blockers d- Barbiturates
i3- Which of the following is a lipid lowering drugs ?i a- Aprotinin b- Tranexamic acid c- Lansoprazole d- Acipimox
i4- Which of the following H2 receptors antagonist has the highest affinity for cytochrome p450 ?i a- Nizatidine b- Ranitidine c- Cimetidine d- Famotidine
i5- Which of the following side effects will be caused by antacids containing NAHCO3?i a- Belching b- Constipation c- Diarrhea d- Blurred vision
i6- Which of the following is a dopamine antagonist?i a- Granisetron b- Domperidone c- Cisapride d- Loperamide
i7- Which of the following drugs is a systemic amoebicide?i a- Diloxamide furoate b- Pyrimethamine c- Emetin d- Sodium Stibogluconate
i8- Which of the following drugs is the drug may cause discolouration of nail beds and mucus membranes?i a- Tetracycline b- Chloroquine c- Doxycycline d- Rifampicin
i9- Which of following drugs is the drug of choice for the treatment of all forms of Schistosomiasis?i a- Praziquantel b- Mebendazole c- Niclosamide d- Thiabendazole
i10- Which of the following drugs can be used for the treatment of influenza A infection ?i a- Zidovudine(AZT)i b- Amantadine c- Ribavarin d- Vidarabine
i11- Which of the following drugs is used in the treatment of Leishmaniasis?i a- Pyrimethamine b- Diloxamide c- Sodium Stibogluconate d- Emetin
i12- Which one of the following statements about tetracycline is not correct?i a- It is useful for the treatment of resistant strains b- It is contraindicated in pregnancy c- It is safe in infections caused by Chlamydia d- It can lead to discolouration of teeth if given to children
i13- Which of the following drug will antagonize Methotrexate?i a- Thiamine b- Folic acid c- Biotin d- Cyanocobalamin
i14- lodine is found in all of the following except:i a- Cod liver oil b- Sea food c- Kelp d- Iodized salt
i15- Match the statements (1- 4) to the trace elements (A-D) listed below.each answer may be used more than once
a- Zinc b- Copper c- Chromium d- Selenium
i1. Formation of red and white blood cells i2. Protects cells against damage during cellular m etabolism i3. Promotes wound healing and normal growth i4. Helps maintain normal glucose m etabolism
i16- Match the drug characteristics (1- 4) with the drug listed below (a-d). each answer may be used more than once a- Auranofin b- Pencillamine c- Aspirin d- Corticosteroids
i1- Platelet function effect i2- Oral form of gold i3- Given on an empty stomach i4- May be given intra articularly
i17- for each side effect (1- 4) list the most likely cause (a-d). each answer may be used more than onces
i1- May cause diarrhea i2- Should not be used by patient of heart failure i3- May cause dry mouth i4- Can be incorporated with an antacids mixture to control diarhoea
i18- Pyridoxine requirements may increase during administration of all the following except:i a- Isoniazid b- Cycloserine c- Oral contraceptives d- Levodopa
i19- All of the following preparations contain alcohol except:i a- Syrup simplex b- Aromatic ammonia spirit USP c- Terpin hydrate elixir USP d- Belladona tincture B.P
i20- Wich of the following solutions is used as an astringent?i a- Strong iodine soluotin USP b- Aluminium acetate topical solution USP c- Acetic acid NF d- Benzalkonium chloride solution NF
21- anextrapyramidal adverse effects is caused by the blocking of:i a- Serotonin receptors in the brain b- Acetylcholine receptors in the brain c- Dopamine receptors in the brain d- Dopamine receptors outside the brain
i22-A rare side effect of some anticonvulsants is Stevens-Johnson syndrome.this is a severe:i a- Skin reaction b- Bone marrow toxicity c- Renal failure d- CNS suppression
i23-If a women,receiving carbamazepine becomes pregnant,it is important that she receives daily supplements of :i a- Vit A b- Vit B6 c- Folic acid d- Riboflavin
i 24-Which of the following are side effects of phenytoin treatment?i a- Acne b- Hirsuitism c- Gingival hyperplasia d- a,b,and c
i25-Which drug is considered as Alpha-1- Adrenergic blocker : i a- Hydralazine b- Minoxidil c- Prazosin d- Guanethidine
i26-Nitroglycerin-all the following are true except :i a- Can be dispensed in hospital pack of 500 and 1000 tabs b- Containers must be made of glass and be covered with a tight-fitting ----l c- Close tightly after use d- Tablets must be stored at controlled R.T e- Tablets not to be refrigerated
i27-The most important adverse reaction to terbutaline is :i a- Tachycardia b- CNS stimulation c- Fine muscle tremor d- Gastric irritation e- All of the above
i28-Which of the following is true about Penicillin V ?i a- It is inactivated by gastric acid b- It is acid stable c- It is more active than Benzylpencillin d- It is absorbed better after foods
i29- Which of the following is a quinolone antibiotic ?i a- Clindamycin b- Chlortetracycline c- Ciprofloxacin d- Clarithromycin
i30-Tuberculosis is caused by a :i a- Mycoplasma b- Mycobacterium c- Micrococcus d- Microbacter
31-pertussis is another name for :i a- Cough b- Diphtheria c- Whooping cough d- Scarlet fever
i32-in the treatment of pulmonary tuberculosis,antibiotic treatment must be continued for at least :i a- 6 months b- 4 months c- 2 months d- 1 month
i33-all of the following are prodrugs except :i a- Sulindac b- Diazepam c- Enalapril d- Sulfasalazine
i34-which route of drug administration is likely to subject a drug to first pass effect ?i a- Intravenous b- Inhalation c- Oral d- Sublingual
i35-which of the following statements is/are correct?i a- Ketamine is used in the treatment of migraine b- Acute systemic anaphylaxis should be treated immediately by IV injection of adrenaline c- Sulphonylureas are oral anticoagulants d- None of the above
i36-verapamil exerts its effects through which of the following actions?i a- Preventing entry of calcium channels through slow channels b- Increasing sodium entry c- Antagonizing the opening of the fast sodium channel d- None of the above
i37-cardiac glycoside may be useful in treating all of the following except :i a- Atrial flutter b- Congestive heart failure c- Ventricular tachycardia d- Atrial fibrillation
i38-streptokinase is indicated for the treatment of :i a- Impaired fat absorption b- Pulmonary emboli c- Tuberculosis d- Psoriasis
i39-tretinoin is used therapeutically :i a- As a urinary acidifier b- As an antifungal agent c- In the treatment of tuberculosis d- In the treatment of acne
i40-a calcium channel blocker that is used parenterally for cardiac arrythmias is :i a- Verapamil hcl b- Nefedipine c- Captopril d- Minoxidil
i41-Wich of the following has not been used for the treatment of Parkinsonism ?i a- Cogentin b- Artane c- Tofranil d- Kemadrin
i42-The drug that is most likely to induce bronchospasm is :i a- Pindolol b- Pentoxyfylline c- Omeprazole d- Lisinopril
i43-The anti-inflammatory effect of aspirin is due to :i a- An anticoagulant effect b- Inhibition of the synthesis of prostaglandins c- An antigen-antibody reaction d- All of the above
i44-The most useful drug in the treatment of diabetes insipidus is :i a- Glibenclamide b- Insulin c- Metoclopramide d- Desmopressin acetate
i45-The tricyclic antidepressant Iimipramine (Tofranil) has been approved by FDA for use in :i a- Parkinson's disease b- Hypertension c- Eneuresis d- Peptic ulcer e- None of the above
i46-Regular use of sublingual doses of Nitroglycerin is likely to result in :i a- Hepatotoxicity b- Nephrotoxicity c- Peptic ulcer d- Tolerance
i47-All of the following are beta blockers except :i a- Metoprolol (Lopressor)i b- Nadolol (Corgard)i c- Enalapril (Renitec)i d- Propranolol (Inderal)i
i48-Bisacodyl frequently can cause :i a- Abdominal cramps b- Constipation c- Skin rashes d- Dizziness
i49-An example of a pure opioid antagonist :i a- Naloxone hcl (Narcan)i b- Pentazocine (Sosegon)i c- Nalbuphine(Nubain)i d- Morphine
i50-Carbamazepine (tegretol) is used for treatment of :i a- Eneuresis b- Trigeminal neuralgia c- Attention of defict disorder d- Psoriasis
51-Buspirone (Buspar) is classified pharmacologically as :i a- Antidepressant b- Anxiolytic agent c- Narcotic analgesic d- Hypnotic
i52-Dilitiazem is used primarily for its ability to produce :i a- Cough depreaaion b- Analgesia c- Calcium channel blockade d- Emesis
i53-Carbocysteine is an agent used clinically as :i a- Laxative b- Cough suppressant c- Diagnostic agent d- Mucolytic
i54-The following drugs may be given by sublingual route except :i a- Digoxin b- Nifedipine c- Nitroglycerin d- Isoprenaline
i55-Match the following antibiotics to the best description given below (a-d)i a- Betalactam antibiotic active against pseudomonas b- Pencillinase resistant betalactam c- Contraindicated in children d- Inhibits renal m etabolism
i56-Disinfectants are expected to destroy or inhibit the growth of microbes which are in :i a- The vegetative stage b- The sporing stage c- Both a and b d- None of the above
i57-Which of the following is not a storage area for iron:i a- Reticuloendothelial system b- Kidney c- Hepatocytes d- Muscle
i58-Which of the following is a sulphonylurea antidiabetic drugs?i a- Chlorpropamide b- Bum etanide c- Acetazolamide d- Frusemide
i59-One drop has a volume of :i a- 0.5 ml b- 0.1 ml c- 0.15 ml d- Variable, depending on the liquid and the dropper
i60-Ketorolac is used in eye preparations as a/an :i a- Anti-inflammatory b- Antihistamine c- Astringent d- Corticosteroid
61-Which of the following drugs is a vasodilator?i a- Methyldopa b- Mexitilline c- Prazocin d- Propranolol
i62-Which of the following drugs is not associated with haemolytic aneamia?i a- Mefenamic acid b- Methyldopa c- Methadone d- Methyl testosterone
i63-Which of the following Vitamins is essential in the formation of Prothrombin?i a- Vitamin A b- Vitamin B complex c- Vitamin E d- Vitamin K
i64-Which of the following is not used as an antitussive ?i a- Noscapine b- Pethidine c- Codeine d- Diphenhydramine
i65-Which of the following Local Anaesthetics is useful for topical administration only?i a- Lidocaine b- Bupivacaine c- Benzocaine d- Procaine
i66-The iron preparation given by the intravenous route is:i a- Ferrous sulphate b- Iron-dextran c- Ferrous gluconate d- Iron-sorbitol citric acid
i67-Carotenoids are precursors for which vitamin?i a- Vitamine E b- Vitamine D c- Vitamine A d- Vitamine K
i68-Which of the following is recommended for dyspepsia in pregnancy?i a- Gaviscon b- Pylorid c- De-nol d- Zantac
i69-Which of the following drug interactions is not used therapeutically?i a- Epinephrine / Lidocaine b- Probenicid / Penicillin c- Pseudoephedrine / Salbutamol d- Trimethoprim / Sulphamethoxazole
i70-The maximum daily dose of Glibenclamide is a- 2.5 mg/day b- 5 mg/day c- 20 mg/day d- 30 mg/day
71-Which of the following is not used to treat psychosis?i
a- Aluoxetine
b- Haloperidol c- Perphenazine d- Resperidone
i72-A sympathomimetic often present in OTC appetite suppressant is:i a- Ephedrine b- Phenylephedrine c- Phenylpropanolamine (PPA)i d- Caffeine
i73-Opioids have the following uses except:i a- Anti tussive b- Anti-inflammatory c- Analgesics d- Pre anaestetics
i74-Levocabastine is a/an:i a- Antihistamine b- Anti microbial c- Anti inflammatory d- Corticosteroid
i75-Which of the following is not used as aprophylaxis for migraine?i a- Pizotifin b- Metoprolol c- Prazocin d- Propranolol
i76-The most common side effect of sublingual glyceryl trinitrate is:i a- Nausea b- Throbbing headache c- Hypertension d- Skin rash
i77-All of the following are common iodine deficiency symptoms except:i a- Goitre b- Intellectual disability c- Growth retardation d- Decreased early and late pregnancy miscarriage
i78-Which of the following insulins has the shortest duration of action?i a- Isophane insulin b- Soluble insulin c- Insulin zinc suspension d- Protamine zinc insulin
i79-Vasopressin (ADH) is used therapeutically for:i a- Treatment of polyuria caused by hypercalceamia b- Treatment of pituitary diabetes insipidus c- Decrease chest pain in refractory unstable angina d- Increasing uterine contractivity
i80-oral sympathomimetic decongestants should be avoided in patients who have:i a- Asthma b- Cough c- Hypertension d- Throat infections
i88-Ketosteroids in urine include :i a- Adrenal and testicular function b- Pituitary function c- Hypothalamic function d- Pancreatic function
i89-Which blood can be safely given to a patient of blood group AB positive?i a- AB negative b- A positive c- B positive d- O positive
i90- Function of gall bladder is :i a- Increase alkalinity of bile b- Increase concentration of bile c- Increase intrabiliary presence d- Increase phosphate level
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