زواج الكبر..خطر قادم يهدد أجيال قادمة

Quote: According to the National Association for Down syndrome, "80% of babies born with Down syndrome are born to women younger than 35. The average maternal age is 28 years old." The likelihood of a woman under 30 years of age giving birth to a child with Down syndrome is less than 1:1000, but increases the older the woman gets (see chart below), with an incidence of about 1:112 at 40 years of age. An annual occurence of Down syndrome of about 9% is seen in women 35 years of age or older, but about 25% of babies with Down syndrome are born to women in this age group. 20-25% of babies conceived with Down syndrome survive past birth. Notification rates to the National Congenital Anomaly System (NCAS) in England and Wales for Down syndrome increased with an increase in maternal age ranging from 3 per 10,000 births for mothers aged 20 to 24 years; 13 per 10,000 for mothers aged 35 to 39 years and 38 per 10,000 for mothers aged 40 years and over