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Re: Statins could reduce the risk of heart attacks and strokes for everyone (Re: Mohamed Omer)
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Matthew Herper is a Senior Editor at Forbes
Missing The Point On Crestor
I think a lot of the debate on the Jupiter study of AstraZeneca's Crestor is way off-base in all sorts of ways, on all sides. But here's a key distinction health wonks and investors should both make. The study will increase statin use and Crestor sales, but not for the same reasons
Jupiter will increase the use of statins (many of them generic) because it provides the strongest evidence yet that a statin will reduce just about anybody's relative risk of getting a heart attack or stroke. So the only question is whether your absolute risk is high enough to justify getting it down
Jupiter will increase sales of Crestor because it shows the drug is effective, adds a halo effect regarding its safety, and, eventually, gives AstraZeneca's sales reps something to talk about in the doctor's office. It will also probably make for some nice direct-to-consumer ads, and may give Crestor an edge over Vytorin from Merck and Schering-Plough, which has not been shown to prevent heart attacks or strokes, in formulary discussions
Crestor doesn't suddenly need to become the main statin for primary prevention. It just needs to grow sales. Not every patient with high C-reactive protein, the blood test used to screen patients for Jupiter, needs to get Crestor. Some will take generics
In fact, Jupiter might also be a gift to Pfizer, because it could lead insurers to favor Lipitor more because Lipitor is almost as potent as Crestor but will be generic in a few years. Merck's Zocor got a big boost right before it went generic as plans started switching patients to the cheaper drug. Could the same thing happen for Pfizer
http://blogs.forbes.com/sciencebizblog/2008/11/missing-the-poi.html
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العنوان |
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Date |
Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-13-08, 11:46 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-13-08, 11:50 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-13-08, 10:23 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-13-08, 11:20 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-13-08, 11:45 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | smart_ana2001 | 11-13-08, 11:50 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-14-08, 06:31 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | jini | 11-14-08, 11:51 PM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 00:38 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 01:38 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 01:41 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 01:43 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 01:52 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 02:04 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 10:08 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 11:46 AM |
Re: Statins could reduce the risk of heart attacks and strokes for everyone | Mohamed Omer | 11-16-08, 05:02 PM |
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